AstraZeneca has warned that it could suffer severe adverse reactions if the cholesterol-lowering drug, Crestor, is used during a treatment with the cholesterol-reducing drug statin.
The drug was approved by the US Food and Drug Administration on November 16, 2010.
In a statement, AstraZeneca said: “AstraZeneca has issued warnings to consumers and healthcare professionals concerning serious adverse reactions to Crestor.”
“We continue to advise people not to take the drug and to seek immediate medical attention if they experience any of the following symptoms, or if they develop a serious adverse reaction, as they may be related to a serious interaction between the drug and the statin,” the statement said.
It said that, in patients with elevated levels of a substance known as “statins”, this could lead to muscle, liver, or kidney problems.
The company said that, “a patient must first have a blood test to check for elevated levels of cholesterol.”
The statement said that, “If the patient has high levels of cholesterol, they should consult their healthcare provider before taking any statin, including any cholesterol-lowering drugs.”
The company said that, “Patients should also be advised that statins can have potential side effects, including increased muscle pain, increased appetite, and muscle weakness.”
The statement said that, “Patients and healthcare providers should consult with their doctor before taking any statin or other medicines to prevent serious side effects or manage the signs and symptoms that may occur.”
AstraZeneca said that, in patients with elevated levels of a substance known as “statins”, this could lead to muscle, liver or kidney problems.
The company said that, in patients with elevated levels of a substance known as “statins”, this could lead to muscle, liver or kidney problems.
“If the patient has high levels of a substance known as “statins,” they should consult their healthcare provider before taking any statin or other medicines to prevent serious side effects or manage the signs and symptoms that may occur.”
AstraZeneca warns against prescribing cholesterol-lowering drug Crestor- -Credit... Image by Flickr user @mike_joints.comAstraZeneca warns against prescribing statin and cholesterol-lowering drug CrestorMedically reviewed by Jessica Swirble, PharmDLast updated on April 18, 2025
Drug Information| | |
Rosuvastatin is a medication classified as a statin, primarily used to lower cholesterol and triglyceride levels in the blood. It belongs to a class of drugs known for their lipid-lowering effects.
Rosuvastatin is used to treat conditions such as:
It's important to note that Rosuvastatin is not suitable for everyone and should not be taken if you have certain underlying cardiovascular conditions.
While it's effective in managing cholesterol and high blood triglycerides, it may not be suitable for individuals with certain metabolic conditions or mental health conditions. Factors that may affect the dose and duration of Rosuvastatin after it is prescribed should you identify include, as well as potential drug and condition interactions.
If you experience symptoms of heart problems or breathing difficulties, such as palpitations or tachycardia, get with it quickly and medicaly relieve these symptoms.
It's also important to ensure that you do not take other medications that could interact with Rosuvastatin such as metoprolol, atorvastigated, lisinopril, flurbipirapine, niacin, vardenafil, and nolvadex. While it's not an cure for cardiovascular conditions, it can help manage symptoms and allow for a decrease in the risk of complications.
The Generic Status of this Drug
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Rosuvastatin belongs to a class of drugs called statins,= commonly used to lower cholesterol and triglyceride levels in the blood. It works by interfering with the enzyme which is required in the body for the proper synthesis of a substance called HMG-CoA reductase.
Rosuvastatin works by reducing the amount of cholesterol in the blood and triglycerides, by inhibiting the enzyme that is responsible for the synthesis of this substance.
It is important to know that Rosuvastatin is an enzyme that has been there and done since at least the 1900's. It is also known as a statin. It is a statin drug that comes in tablet form and is taken as a pill. It’s important to know that Rosuvastatin does not work as effectively when taken with high cholesterol medication.
Rosuvastatin is taken orally with a glass of water, with or without food.
As with any medication, there are side effects to consider.
CRESTOR 10MG TABLET is used in the management of high blood cholesterol levels. It is prescribed when diet and exercise does not result in adequate results. It contains a medicine called which is an anti-hyperlipidemic agent that works by blocking cholesterol production in the body. It also makes your body eliminate lipids particles from the blood.
By reducing blood cholesterol levels, this medicine is helpful is reducing cardiovascular risks and problems in blood circulation across the body. While taking CRESTOR 10MG TABLET, you must follow a cholesterol-lowering diet, lifestyle changes and regular physical activity as instructed by your doctor to achieve better results.
Before taking CRESTOR 10MG TABLET inform your doctor if you have any lung, liver, kidney or heart problems. You must also inform your doctor if you have diabetes, thyroid problems, or a family history of muscle disorders. Do not take CRESTOR 10MG TABLET if you are pregnant or breastfeeding without consulting your doctor.
CRESTOR 10MG TABLET may increase your blood sugar levels, especially in patients who are diabetic. It may also affect the way your liver works and so your doctor will closely monitor your blood sugar levels and liver functions while undergoing therapy with CRESTOR 10MG TABLET as a precaution.
The most common side effects of taking CRESTOR 10MG TABLET are muscle ache, constipation, stomach pain, dizziness, nausea and headache. Inform your doctor if you experience severe unexplained muscle pain, tenderness or weakness along with fever after taking CRESTOR 10MG TABLET.
Tell your doctor if you have any kidney or liver problems. Do not also take CRESTOR 10MG TABLET if you are pregnant or breastfeeding. While taking CRESTOR 10MG TABLET, you must follow a cholesterol-lowering diet, lifestyle changes and regular physical activity as instructed by your doctor. Take CRESTOR 10MG TABLET with a full glass of water or other liquids before eating fat.CRESTOR 10MG TABLET may increase the risk of getting tendon rupture. If you experience sudden numbness or numbness in extremities viapi Fe or eversible decrease in function of the elbow is unlikely. However, if theAPIFEAK sign is used the patient should consult a doctor before taking this medication. Inform your doctor if you experience severe or unwanted muscle pain, tenderness or weakness along with fever after taking CRESTOR 10MG TABLET.
CRESTOR 10MG TABLET may increase the risk of getting stomach ulcers. If you experience sudden numbness or numbness in extremities asucklebe ease feel feel pain in groin pain while taking this medication. However, the most common side effects are muscle pain, tenderness or weakness along with fever after taking CRESTOR 10MG TABLET.
CRESTOR 10MG TABLET is used in the management of high blood cholesterol levels. It is prescribed when diet and exercise does not result in adequate results. It contains a medicine called which is an anti-hyperlipidemic agent that works by blocking cholesterol production in the body. It also makes your body eliminate lipids particles from the blood.
By reducing blood cholesterol levels, this medicine is helpful is reducing cardiovascular risks and problems in blood circulation across the body. While taking CRESTOR 10MG TABLET, you must follow a cholesterol-lowering diet, lifestyle changes and regular physical activity as instructed by your doctor to achieve better results.
Before taking CRESTOR 10MG TABLET inform your doctor if you have any lung, liver, kidney or heart problems. You must also inform your doctor if you have diabetes, thyroid problems, or a family history of muscle disorders. Do not take CRESTOR 10MG TABLET if you are pregnant or breastfeeding without consulting your doctor.
CRESTOR 10MG TABLET may increase your blood sugar levels, especially in patients who are diabetic. It may also affect the way your liver works and so your doctor will closely monitor your blood sugar levels and liver functions while undergoing therapy with CRESTOR 10MG TABLET as a precaution.
The most common side effects of taking CRESTOR 10MG TABLET are muscle ache, constipation, stomach pain, dizziness, nausea and headache. Inform your doctor if you experience severe unexplained muscle pain, tenderness or weakness along with fever after taking CRESTOR 10MG TABLET.
How should I take CRESTOR 10MG TABLET? CRESTOR 10MG TABLET should be used only when high-dose capsules are not needed. Do not take it lower the dose if you have severe kidney or liver problems. Swallow this medicine with a glass of water before each and after eating Staying hydrated while taking CRESTOR 10MG TABLET is not normal and should be used to manage high blood cholesterol levels. It is important to note that CRESTOR 10MG TABLET should not be used in the treatment of kidney or liver problems.The most common side effects of taking CRESTOR 10MG TABLET are muscle pain, tenderness or weakness, non-adverse effects, etc. Some of them include but are not limited to: headache, dizziness, trouble sleeping, decreased appetite, increased heartbeat, increased appetite,itaemia,joint pain,)?, stomach pain,)? itching or discharge,)? leg cramps or stiffness,)? pain or stiffness, muscle ache, shouldn't be treated by a doctor
The following are potential side effects of taking CRESTOR 10MG TABLET: Fatigue, weakness, numbness or tingling skin, confusion, photosensitivity, peripheral arterial pressure (PAP) estimation may need to be adjusted while taking CRESTOR 10MG TABLET to be effective: Photosensitivity may need to be further investigated and/or treated while taking CRESTOR 10MG TABLET.
In rare cases, CRESTOR 10MG TABLET can cause other conditions, such as multiple sclerosis (also called a spinal cancer), it can cause blurred vision, muscle pain, tingling in the arms or legs, rashes or drowsiness, should use caution when experiencing symptoms of a muscle pain or pain with elevated blood-sugar levels, while undergoing therapy with CRESTOR 10MG TABLET.
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Healthy lifestyle changes and CRESTOR 10MG TABLET can help reduce the risk of some health complications in patients with diabetes, while also offering relief against hyperlipidemia.
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Diabetes is a common condition that can cause changes in blood sugar levels, which can affect cholesterol, blood weight and blood cholesterol profiles.
Chloramphenicol
The use of this drug is contraindicated because the use of chloramphenicol will increase the effect of Sildenafil by affecting the patient hepatic and intestinal enzyme metabolism. If the action of Sildenafil becomes impaired, the drug will causeermanent changes in the pharmacokinetics of valsartan. Also, the pharmacological effects of Sildenafil should be carefully considered in patients with mild to severe liver impairment.
Isosorbide dinitrate
The use of this drug is contraindicated because the combination of isosorbide dinitrate and tablets of this drug will result in a serious drop in the total blood pressure. Also, the mycoplasma pneumoniae agent will continue to be the cause of pneumonia with the integration of isosorbide dinitrate and tablets of this drug. The combined administration of isosorbide dinitrate and tablets of this drug will result in a serious drop in the total blood pressure. Use of this drug during or within 4 months after the last mycoplasma test is complete may result in a serious drop in the mycoplasma pneumoniae index. Also, the mycoplasma pneumoniae index can be influenced by the dosage and duration of treatment.
Potassium-sparing diuretics
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